Comment
doi: 10.1016/j.immuni.2006.08.013.
Transforming growth factor-beta: taking control of T cells' life and death
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- PMID: 16979574
- DOI: 10.1016/j.immuni.2006.08.013
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Comment
Transforming growth factor-beta: taking control of T cells' life and death
Immunity.
2006 Sep.
Free article
Abstract
To determine how transforming growth factor-beta (TGF-beta) controls T cell function, Marie et al. (2006) and Li et al. (2006a) created mice with T cells lacking TGF-beta signaling receptors. Both report that TGF-beta signaling by T cells is absolutely essential for tolerance and homeostasis.
Comment on
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Transforming growth factor-beta controls development, homeostasis, and tolerance of T cells by regulatory T cell-dependent and -independent mechanisms.Immunity. 2006 Sep;25(3):455-71. doi: 10.1016/j.immuni.2006.07.011. Immunity. 2006. PMID: 16973386
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Cellular mechanisms of fatal early-onset autoimmunity in mice with the T cell-specific targeting of transforming growth factor-beta receptor.Immunity. 2006 Sep;25(3):441-54. doi: 10.1016/j.immuni.2006.07.012. Immunity. 2006. PMID: 16973387
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