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Comment
. 2006 Sep;25(3):399-401.
doi: 10.1016/j.immuni.2006.08.013.

Transforming growth factor-beta: taking control of T cells' life and death

David A Horwitz  1
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Free article
Comment

Transforming growth factor-beta: taking control of T cells' life and death

David A Horwitz. Immunity. 2006 Sep.
Free article

Abstract

To determine how transforming growth factor-beta (TGF-beta) controls T cell function, Marie et al. (2006) and Li et al. (2006a) created mice with T cells lacking TGF-beta signaling receptors. Both report that TGF-beta signaling by T cells is absolutely essential for tolerance and homeostasis.

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