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Review
. 2006 Oct 1;58(8):902-15.
doi: 10.1016/j.addr.2006.05.004. Epub 2006 Aug 7.

Challenges for cancer vaccine development

Z Tabi  1 , S Man
Affiliations
Review

Challenges for cancer vaccine development

Z Tabi et al. Adv Drug Deliv Rev. .

Abstract

The first generation of human cancer vaccines has been tested in phase III clinical trials, but only a few of these have demonstrated sufficient efficacy to be licensed for clinical use. This article reviews some of the mechanisms that could contribute to these limited clinical responses, and highlights the challenges faced for development of future vaccines.

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