Review
doi: 10.1186/cc5019.
Antimicrobial resistance and patient outcomes: the hazards of adjustment
Affiliations
- PMID: 16982010
- PMCID: PMC1751076
- DOI: 10.1186/cc5019
Item in Clipboard
Review
Antimicrobial resistance and patient outcomes: the hazards of adjustment
Crit Care.
2006.
Abstract
Outcomes studies of infections with resistant bacteria often do not account appropriately for intermediate variables--events in the causal pathway between the exposure and the outcome--when controlling for confounders. We discuss how failure to distinguish between confounders and intermediate variables can bias the analysis, and we address methods of approaching this issue.
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