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. 2006 Dec;50(12):4224-8.
doi: 10.1128/AAC.00904-06. Epub 2006 Sep 18.

qnrA in CTX-M-producing Escherichia coli isolates from France

Jean-Philippe Lavigne  1 , Hélène Marchandin, Julien Delmas, Nicole Bouziges, Evelyne Lecaillon, Laurent Cavalie, Hélène Jean-Pierre, Richard Bonnet, Albert Sotto
Affiliations

qnrA in CTX-M-producing Escherichia coli isolates from France

Jean-Philippe Lavigne et al. Antimicrob Agents Chemother. 2006 Dec.

Abstract

By PCR, we screened for qnr genes 112 clinical isolates of extended-spectrum beta-lactamase-producing Escherichia coli collected from hospitals in France during 2004. For the first time, 7.7% of CTX-M-producing E. coli isolates presented a plasmid-mediated resistance to quinolones. All strains harbored a qnrA gene located on a sul1-type class 1 integron with similar structure to the In36 integron.

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Figures

FIG. 1.
FIG. 1.
Distribution of ESBL-producing Escherichia coli strains found in four hospitals in France.
FIG. 2.
FIG. 2.
Dendrogram of XbaI-digested genomic DNAs from all of the CTX-M-15-producing E. coli strains isolated in four hospitals in France. MTP, Montpellier; CF, Clermont-Ferrand; NEC, Nîmes; and PEC, Perpignan. Strains were clustered by the unweighted-pair group method using arithmetic averages (UPGMA). The scale indicates the percentage of genetic similarity. Max. tol., percent maximum tolerance of the curve that matches the bands; Min. surf., percent minimum surface area of a band. The four strains harboring the qnrA gene are noted with asterisks.
See this image and copyright information in PMC

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