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. 2006 Dec;50(12):4177-81.
doi: 10.1128/AAC.00619-06. Epub 2006 Sep 18.

Genetic environment of acquired bla(ACC-1) beta-lactamase gene in Enterobacteriaceae isolates

A Doloy  1 , C Verdet, V Gautier, D Decré, E Ronco, A Hammami, A Philippon, G Arlet
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Genetic environment of acquired bla(ACC-1) beta-lactamase gene in Enterobacteriaceae isolates

A Doloy et al. Antimicrob Agents Chemother. 2006 Dec.

Abstract

We studied the genetic organization of bla(ACC-1) in 14 isolates of Enterobacteriaceae from France, Tunisia, and Germany. In a common ancestor, ISEcp1 was likely involved in the mobilization of this gene from the Hafnia alvei chromosome to a plasmid. Other genetic events involving insertion sequences (particularly IS26), transposons (particularly Tn1696), or sulI-type integrons have occurred, leading to complex genetic environments.

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Figures

FIG. 1.
FIG. 1.
Comparison of regions surrounding blaACC-1. ORF, open reading frame.
See this image and copyright information in PMC

References

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