Comment on

• Structural basis for macrolactonization by the pikromycin thioesterase.

  Akey DL, Kittendorf JD, Giraldes JW, Fecik RA, Sherman DH, Smith JL. Akey DL, et al. Nat Chem Biol. 2006 Oct;2(10):537-42. doi: 10.1038/nchembio824. Epub 2006 Sep 10. Nat Chem Biol. 2006. PMID: 16969372
• Structural and mechanistic insights into polyketide macrolactonization from polyketide-based affinity labels.

  Giraldes JW, Akey DL, Kittendorf JD, Sherman DH, Smith JL, Fecik RA. Giraldes JW, et al. Nat Chem Biol. 2006 Oct;2(10):531-6. doi: 10.1038/nchembio822. Epub 2006 Sep 10. Nat Chem Biol. 2006. PMID: 16969373