Prognostic value of initial magnetic resonance imaging growth rates for World Health Organization grade II gliomas
- PMID: 16983683
- DOI: 10.1002/ana.20946
Prognostic value of initial magnetic resonance imaging growth rates for World Health Organization grade II gliomas
Abstract
A consecutive series of 143 unselected adult patients with histologically proved World Health Organization grade II gliomas was reviewed to assess the prognostic value of growth rates of mean tumor diameters on successive magnetic resonance images before treatment. There is an inverse correlation between growth rates and survival (p < 0.001; median survival at 5.16 years for a growth rate of 8mm/year or more; median survival >15.0 years for a growth rate <8mm/year). Thus, individual magnetic resonance imaging tumor growth rates should be incorporated in the planning of the initial therapeutic strategy of grade II gliomas.
Comment in
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Using mathematical modeling to predict survival of low-grade gliomas.Ann Neurol. 2007 May;61(5):496; author reply 496-7. doi: 10.1002/ana.21042. Ann Neurol. 2007. PMID: 17252546 No abstract available.
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Is the volume of low-grade glioma measurable and is it clinically relevant?Neuro Oncol. 2014 Aug;16(8):1027-8. doi: 10.1093/neuonc/nou119. Epub 2014 Jun 20. Neuro Oncol. 2014. PMID: 24951113 Free PMC article. No abstract available.
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