Comment
doi: 10.1016/j.chembiol.2006.09.002.
A noncanonical path to mechanism of action
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- PMID: 16984880
- DOI: 10.1016/j.chembiol.2006.09.002
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Comment
A noncanonical path to mechanism of action
Chem Biol.
2006 Sep.
Abstract
Improved methods for discovering small-molecule mechanisms of action are needed. In this issue of Chemistry & Biology, Zhang et al. make clever use of the zebrafish to study the mechanism of the angiogenesis inhibitor fumagillin and reveal that it targets the noncanonical Wnt pathway.
Comment on
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A chemical and genetic approach to the mode of action of fumagillin.Chem Biol. 2006 Sep;13(9):1001-9. doi: 10.1016/j.chembiol.2006.07.010. Chem Biol. 2006. PMID: 16984890 Free PMC article.
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