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. 2003 Summer;5(3):135-41.

Pharmacotherapy for stress urinary incontinence

Tracy W Cannon, Michael B Chancellor

Pharmacotherapy for stress urinary incontinence

Tracy W Cannon et al. Rev Urol. 2003 Summer.

Abstract

The purpose of this review article is to highlight new pharmacotherapies on the horizon for the treatment of stress urinary incontinence. Although behavioral and surgical therapies are currently the mainstay of treatment for this condition, we are hopeful that pharmacotherapy will one day take center stage of the various treatment options. Currently, there are no medications approved by the US Food and Drug Administration for the treatment of stress urinary incontinence. However, exciting clinical data are becoming available about an oral medication for the treatment of stress urinary incontinence that appears to be clinically safe and efficacious. In addition to discussing medications currently under development, this article also discusses pharmacologic targets that could be suitable future targets to treat stress urinary incontinence.

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Figures

Figure 1
Figure 1
Sympathetic and parasympathetic control of urethral smooth muscle. Red and green arrows indicate inhibition and excitation, respectively.
Figure 2
Figure 2
Somatic control of the external urethral sphincter.
Figure 3
Figure 3
Monoaminergic synapse, illustrating monoamine reuptake from the synaptic cleft and monamine reuptake inhibition.
See this image and copyright information in PMC

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