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Review
. 2006 Aug;6(3):43-7.
doi: 10.17305/bjbms.2006.3143.

Immunosuppressive therapy protocols in kidney transplantation in adults

Jasenko Karamehić  1 , Marc Lorber, Richard Formica, Faris Gavrankapetanović, Bećir Heljić, Demo Subasić, Lamija Zecević
Affiliations
Review

Immunosuppressive therapy protocols in kidney transplantation in adults

Jasenko Karamehić et al. Bosn J Basic Med Sci. 2006 Aug.

Abstract

In practical terms, regardless of HLA compatibility level, whenever tissues are transplanted from one person to another it is essential to suppress the immune response of the recipient. A variety of methods are available however, the most frequently used ones have the disadvantage of being immunologicaly non specific. The consequence is a difficult balance between immunosuppression sufficient to prevent the tissue rejection and maintenance of immune system at the level of ability to adequately deal with an infection. The goal, not yet achieved, is to find a way of generating donor specific immunosuppression that leaves the immune machinery otherwise completely intact. The major approaches to immunosuppression are described below.

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Figures

FIGURE 1
FIGURE 1
Vascular rejection in kidney transplant (Acute rejection).
FIGURE 2
FIGURE 2
Acute tubulitis (Acute rejection).
FIGURE 3
FIGURE 3
Transplant glomerulopathy with slight mesangial matrix increase in transplant nephropathy (Acute rejection).
FIGURE 4
FIGURE 4
Transplant glomerulopathy with no mesangial matrix increase (Acute rejection).
FIGURE 5 and 6
FIGURE 5 and 6
PAS positive nodular hyaline thickening in CsA toxicity in kidney transplant (Chronic rejection)
See this image and copyright information in PMC

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