Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2006 Dec;50(12):4220-3.
doi: 10.1128/AAC.00300-06. Epub 2006 Sep 25.

Molecular epidemiology of VIM-4 metallo-beta-lactamase-producing Pseudomonas sp. isolates in Hungary

Balázs Libisch  1 , Mónika Muzslay, Mária Gacs, János Minárovits, Márta Knausz, Joseph Watine, Gábor Ternák, Eva Kenéz, Ildikó Kustos, László Rókusz, Klára Széles, Boglárka Balogh, Miklós Füzi
Affiliations

Molecular epidemiology of VIM-4 metallo-beta-lactamase-producing Pseudomonas sp. isolates in Hungary

Balázs Libisch et al. Antimicrob Agents Chemother. 2006 Dec.

Abstract

VIM metallo-beta-lactamase-producing serotype O11 or O12 Pseudomonas aeruginosa isolates infecting or colonizing 19 patients from seven hospitals in Hungary were characterized between October 2003 and November 2005. Macrorestriction analysis revealed the involvement of hospitals from three different towns in northwest Hungary in an outbreak caused by VIM-4-producing P. aeruginosa.

PubMed Disclaimer

Figures

FIG. 1.
FIG. 1.
Geographic distribution of the VIM-positive P. aeruginosa clinical isolates in Hungary characterized in the present study. Small black circles indicate the cities. Budapest (the capital) is underlined. Mosonm., Mosonmagyaróvár. The serotype and PFGE subtype of the VIM-positive P. aeruginosa isolates characterized are shown under or next to the names of the cities.
FIG. 2.
FIG. 2.
Comparison of the schematic structures of the blaVIM-4-carrying class 1 integrons from Hungary. Open ellipses, attI1 site; black circles, 59-base elements; asterisks, blaVIM-4 cassettes with the 170-bp duplication; 5′-CS and 3′-CS, 5′ and 3′ conserved sequences, respectively. GenBank accession numbers and isolates harboring the integrons are as follows: (a) AY509609 and isolate PA396, (b) AY702100 and isolate PA555, (c) isolate MB387, (d) DQ357197 and isolate MB197.
See this image and copyright information in PMC

References

    1. Clinical and Laboratory Standards Institute. 2005. Performance standards for antimicrobial susceptibility testing. Fifteenth informational supplement. M100-S15. Clinical and Laboratory Standards Institute, Wayne, Pa.
    1. Crespo, M. P., N. Woodford, A. Sinclair, M. E. Kaufmann, J. Turton, J. Glover, J. D. Velez, C. R. Castaneda, M. Recalde, and D. M. Livermore. 2004. Outbreak of carbapenem-resistant Pseudomonas aeruginosa producing VIM-8, a novel metallo-β-lactamase, in a tertiary care center in Cali, Colombia. J. Clin. Microbiol. 42:5094-5101. - PMC - PubMed
    1. Fiett, J., A. Baraniak, A. Mrowka, M. Fleischer, Z. Drulis-Kawa, L. Naumiuk, A. Samet, W. Hryniewicz, and M. Gniadkowski. 2006. Molecular epidemiology of acquired-metallo-β-lactamase-producing bacteria in Poland. Antimicrob. Agents Chemother. 50:880-886. - PMC - PubMed
    1. Grattard, F., O. G. Gaudin, B. Pozzeto, A. Ris, and A. D. Mbida. 1993. Genotypic homogeneity of nosocomial Pseudomonas aeruginosa O12 strains demonstrated by analysis of protein profiles, DNA fingerprints and rRNA gene restriction patterns. Eur. J. Clin. Microbiol. Infect. Dis. 12:57-61. - PubMed
    1. Johan Béla National Public Health Institute. 1997. Antibiotic susceptibility of the most important gram-negative bacteria, p. 159-173. In The 1996 annual report of the Johan Béla National Public Health Institute. Johan Béla National Public Health Institute, Budapest, Hungary. (In Hungarian.)

Publication types

Substances

Associated data

LinkOut - more resources