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Review
. 1990 Oct;13(10):420-3.
doi: 10.1016/0166-2236(90)90124-s.

The cannabinoid receptor: biochemical, anatomical and behavioral characterization

A C Howlett  1 , M Bidaut-Russell, W A Devane, L S Melvin, M R Johnson, M Herkenham
Affiliations
Review

The cannabinoid receptor: biochemical, anatomical and behavioral characterization

A C Howlett et al. Trends Neurosci. 1990 Oct.

Abstract

The actions of the active principle of marihuana, delta 9-tetrahydrocannabinol, are mimicked by synthetic cannabinoid agonists showing high potency and enantio-selectivity in behavioral assays. These drugs have been used to characterize cannabinoid receptor binding, biochemistry and pharmacology, leading to a better understanding of the effects of cannabinoids in the CNS of humans and experimental animals.

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