Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2006 Nov 24;281(47):35593-7.
doi: 10.1074/jbc.R600027200. Epub 2006 Sep 27.

Re-solving the cadherin-catenin-actin conundrum

Affiliations
Review

Re-solving the cadherin-catenin-actin conundrum

William I Weis et al. J Biol Chem. .
No abstract available

PubMed Disclaimer

Figures

FIGURE 1
FIGURE 1. Models of how the cadherin-catenin complex is linked to and regulates the actin cytoskeleton
A, model based upon the assumption that α-catenin binds simultaneously to β-catenin and actin filaments. B, model based upon data from Refs and that α-catenin monomers and dimers regulate binding to β-catenin and actin filaments, respectively, and that α-catenin also inhibits Arp2/3-mediated actin branching and promotes actin bundling. See text for details.

Similar articles

Cited by

References

    1. Takeichi M. Curr Opin Cell Biol. 1995;7:619–627. - PubMed
    1. Gumbiner BM. Nat Rev Mol Cell Biol. 2005;6:622–634. - PubMed
    1. Larue L, Antos C, Butz S, Huber O, Delmas V, Dominis M, Kemler R. Development. 1996;122:3185–3194. - PubMed
    1. Wang F, Dumstrei K, Haag T, Hartenstein V. Dev Biol. 2004;270:350–363. - PubMed
    1. Nose A, Nagafuchi A, Takeichi M. Cell. 1988;54:993–1001. - PubMed

Publication types