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Comment
. 2006 Oct 3;103(40):14649-50.
doi: 10.1073/pnas.0606951103. Epub 2006 Sep 27.

Tumors reveal their secrets to cytotoxic T cells

Affiliations
Comment

Tumors reveal their secrets to cytotoxic T cells

Nicholas A Williamson et al. Proc Natl Acad Sci U S A. .
No abstract available

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Fig. 1.
Fig. 1.
A structural model of HLA A2 complexed to the RTLpSHISEA peptide. The structure was modeled on the structure of HLA A2 complexed to the tumor-antigen-derived peptide NY-ESO 157–165 (SLLMWITQC) (12). The peptide sequence of NY-ESO 157–165 was mutated to the RTLpSHISEA sequence, and the phosphoserine moiety (shown in yellow) was introduced before energy minimization by using the CNS software package (13).

Comment on

References

    1. Engelhard VH, Altrich-Vanlith M, Ostankovitch M, Zarling AL. Curr Opin Immunol. 2006;18:92–97. - PubMed
    1. Zarling AL, Polefrone JM, Evans AM, Mikesh LM, Shabanowitz J, Lewis ST, Engelhard VH, Hunt DF. Proc Natl Acad Sci USA. 2006;103:14889–14894. - PMC - PubMed
    1. Tynan FE, Burrows SR, Buckle AM, Clements CS, Borg NA, Miles JJ, Beddoe T, Whisstock JC, Wilce MC, Silins SL, et al. Nat Immunol. 2005;6:1114–1122. - PubMed
    1. Mayordomo JI, Loftus DJ, Sakamoto H, De Cesare CM, Appasamy PM, Lotze MT, Storkus WJ, Appella E, DeLeo AB. J Exp Med. 1996;183:1357–1365. - PMC - PubMed
    1. Gottschalk S, Heslop HE, Rooney CM. Leuk Lymphoma. 2005;46:1–10. - PubMed

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