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Case Reports
. 2006 Dec;44(12):4619-22.
doi: 10.1128/JCM.01019-06. Epub 2006 Sep 27.

Phaeoacremonium krajdenii, a cause of white grain eumycetoma

B M Hemashettar  1 , B Siddaramappa, B S Munjunathaswamy, A S Pangi, Jayashree Pattan, A T Andrade, A A Padhye, Lizel Mostert, R C Summerbell
Affiliations
Case Reports

Phaeoacremonium krajdenii, a cause of white grain eumycetoma

B M Hemashettar et al. J Clin Microbiol. 2006 Dec.

Abstract

We describe the first case of white grain pedal eumycetoma caused by Phaeoacremonium krajdenii in a 41-year-old man from Goa, India. Based on histological examination of biopsy tissue showing serpentine granules, a culture of the granules yielding phaeoid fungal colonies, and morphological characteristics and sequence comparison of the partial beta-tubulin gene with the ex-type isolate of P. krajdenii, the causal agent was identified as P. krajdenii.

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Figures

FIG. 1.
FIG. 1.
(A) Mycetoma on the right foot of the patient showing discharging sinuses on the dorsal aspect of the foot. (B) Tissue section showing a serpentine granule of Phaeoacremonium krajdenii. Stain, H&E. Magnification, ×483. (C) Magnified portion of the granule showing a Splendore-Hoeppli reaction. Stain, H&E. Magnification, ×772. (D) Portion of the granule showing intertwined hyphal elements and vesiculate chlamydospores. Stain, GMS. Magnification, ×772. (E) Slide culture of P. krajdenii (CDC B-6093 is CBS 110361) showing mono- and polyphialides of cylindrical to elongate-ampulliform shapes and ellipsoidal to allantoid conidia. Magnification, ×772. 1, 2, and 3, first, second, and third types of phialides as described in the text; arrows, collarettes.
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