IL-10: Another therapeutic target in idiopathic pulmonary fibrosis?
- PMID: 17008481
- PMCID: PMC2104749
- DOI: 10.1136/thx.2006.060772
IL-10: Another therapeutic target in idiopathic pulmonary fibrosis?
Abstract
The need for appropriately designed clinical trials in IPF
Conflict of interest statement
Competing interests: none declared.
Comment on
-
In vivo IL-10 gene delivery attenuates bleomycin induced pulmonary fibrosis by inhibiting the production and activation of TGF-beta in the lung.Thorax. 2006 Oct;61(10):886-94. doi: 10.1136/thx.2005.056317. Epub 2006 Jun 29. Thorax. 2006. PMID: 16809410 Free PMC article.
References
-
- Raghu G, Brown K K, Bradford W Z.et al A placebo‐controlled trial of interferon gamma‐1β in patients with idiopathic pulmonary fibrosis. N Engl J Med 2004350125–133. - PubMed
-
- Azuma A, Nukiwa T, Tsuboi E.et al Double‐blind, placebo‐controlled trial of pirfenidone in patients with idiopathic pulmonary fibrosis. Am J Respir Crit Care Med 20051711040–1047. - PubMed
-
- Demedts M, Behr J, Buhl R.et al High‐dose acetylcysteine in idiopathic pulmonary fibrosis. N Engl J Med 20053532229–2242. - PubMed
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical