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Review
. 2006 Sep;68(3):463-9.
doi: 10.1016/j.urology.2006.03.069.

Drug delivery systems in urology--getting "smarter"

Omid C Farokhzad  1 , Jordan D Dimitrakov, Jeffrey M Karp, Ali Khademhosseini, Michael R Freeman, Robert Langer
Affiliations
Review

Drug delivery systems in urology--getting "smarter"

Omid C Farokhzad et al. Urology. 2006 Sep.
No abstract available

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Figures

Figure 1
Figure 1
Time series of photographs showing recovery of a shape-memory tube. a–f, Start to finish of the process; total time, 10 seconds at 50°C. The tube was made of a poly(epsilon-caprolactone) dimethacrylate polymer network that had been programmed to form a flat helix. (Reproduced with permission from Langer and Tirrell8)
Figure 2
Figure 2
Design of nanoparticle-drug conjugates involves combining drug laden materials, such as biodegradable polymers, with a targeting moiety. The polymer should have functional groups for the attachment of targeting moieties (which may be bound directly to the surface or though a spacer group) and of molecules to enhance the half-life in circulation (i.e. poly(ethylene glycol)).
Figure 3
Figure 3
Non-Degradable microchip device for pulsatile release of multiple substances (Reproduced with permission from Santini et al40)
Figure 4
Figure 4
Degradable microchip device for pulsatile release of multiple substances. (Reproduced with permission from Richards et al46)
See this image and copyright information in PMC

References

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