[Lipometabolic disorder--cholesterol and triglycerides]

Abstract

Resorption inhibitors for cholesterol are commonly applied today in case of hypercholesterolemia in addition to statins. This combination therapy reduces the value of the LDL concentration by 50-60%. A target value of 100 mg/dl should be adjusted in case of high-risk patients in order to also decrease coronary risk. The significance of the triglycerides level is also becoming increasingly important, for it describes a high cardiovascular risk due to an increase of adiposity and diabetes. Such a dysfunction in storage and release of fatty lipids from triglycerides is treated dependent on severity: Patients with slightly elevated values (> 200 mg/dl) should change their habits (e.g. balanced diet, abstinance of alcohol, exercise) if necessary followed by application of fibrates, omega-3 fatty acids or nicotinic acid. These medicamentous measures are inevitable and must be applied immediately in case patients having values >1000 mg/dl.