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. 2005;50(8-9):43-51.

[Problems of prevalance and resistance of nosocomial Klebsiella pneumonia in hospitals of Russia]

[Article in Russian]
E L Riabkova, G K Reshed'ko, E D Agapova, I A Aleksandrova, N V Beloborodova, T Iu Vostrikova, D E Zdzitovetskiĭ, S F Ivanova, V N Il'ina, N E Marusina, I G Multykh, S V Polikarpova, S V Skal'skiĭ, T N Suborova, I A Toropova, V B Turkutiukov
  • PMID: 17016911

[Problems of prevalance and resistance of nosocomial Klebsiella pneumonia in hospitals of Russia]

[Article in Russian]
E L Riabkova et al. Antibiot Khimioter. 2005.

Abstract

Prevalence of Klebsiella pneumoniae among gramnegative pathogens of nosocomial infections in intensive care units of 33 hospitals of 22 towns in Russia was investigated. Antibiotic susceptibility and extended-spectrum beta-lactamase production were tested in 420 nosocomial K. pneumoniae isolates. Carbapenems (imipenem, meropenem and ertapenem) showed the highest activity. Extended-spectrum beta-lactamase production based on the phenotyping methods was revealed in 342 (81.4%) isolates. The maximum activity against the K. pneumoniae isolates producing extended-spectrum beta-lactamase was observed in imipenem and meropenem (no unsusceptible strains were isolated). 3.2% of the isolates was not susceptible to ertapenem. Differences in the activity of cefoperazone/sulbactam, amikacin, ciprofloxacin and levofloxacin against the extended-spectrum beta-lactamase producing isolates in various hospitals were recorded.

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