Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2006;23(3):419-22.
doi: 10.1385/MO:23:3:419.

Pemetrexed-induced acute renal failure, nephrogenic diabetes insipidus, and renal tubular acidosis in a patient with non-small cell lung cancer

Vidya Vootukuru  1 , Yin Ping Liew, Joseph V Nally Jr
Affiliations
Case Reports

Pemetrexed-induced acute renal failure, nephrogenic diabetes insipidus, and renal tubular acidosis in a patient with non-small cell lung cancer

Vidya Vootukuru et al. Med Oncol. 2006.

Abstract

We report a patient with metastatic non-small cell lung cancer who developed renal toxicities manifest as acute renal failure associated with nephrogenic diabetes insipidus and distal renal tubular acidosis following sequential therapy with pemetrexed. The nephrotoxicity occurred concomitantly with severe myelosuppression. We postulate renal tubular toxicity may account for distinct patterns of injury including acute renal failure and tubular cell dysfunction of the distal nephron.

PubMed Disclaimer

References

    1. Cancer Chemother Pharmacol. 1999;44(5):372-80 - PubMed
    1. Oncologist. 2004;9(5):482-8 - PubMed
    1. Semin Oncol. 2005 Apr;32(2 Suppl 2):S16-22 - PubMed

Publication types

MeSH terms

LinkOut - more resources