The anterior ectosylvian sulcal auditory field in the cat: II. A horseradish peroxidase study of its thalamic and cortical connections

Abstract

The thalamic and cortical projections to acoustically responsive regions of the anterior ectosylvian sulcus were determined by identifying retrogradely labelled cells after physiologically guided iontophoretic injections of horseradish peroxidase. The medial division of the medial geniculate nucleus, the intermediate division of the posterior nuclear group, the principal division of the ventromedial nucleus, and the lateroposterior complex were consistently labelled after these injections, although each animal showed slightly different patterns of labelling. The suprageniculate nucleus and the lateral and medial divisions of the posterior nuclear group were also labelled in most experiments. The cortex of the suprasylvian sulcus was the most consistently and densely labelled cortical region; each experiment showed a slightly different pattern of labelling throughout the suprasylvian sulcus, with an overall tendency for greater labelling in the ventral (lateral) bank of the middle region of the sulcus. Other cortical regions labelled less consistently included the anterior ectosylvian sulcus itself, the insular cortex of the anterior sylvian gyrus, and the posterior rhinal sulcus. In three experiments the contralateral cortex was examined and a small number of labelled cells was located in the anterior ectosylvian and suprasylvian sulci. Input from extralemniscal auditory thalamus is compatible with previously described auditory response properties of anterior ectosylvian sulcus neurons. The results also confirm the presence of input from visual and multimodal regions of thalamus and cortex, and therefore support claims of overlap of modalities within the sulcus. This overlap, as well as input from motor regions, suggests that the anterior ectosylvian sulcal field serves a sensorimotor role.