Antibiotic blocks mRNA path on the ribosome
- PMID: 17021617
- DOI: 10.1038/nsmb1006-858
Antibiotic blocks mRNA path on the ribosome
Comment on
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Structural analysis of kasugamycin inhibition of translation.Nat Struct Mol Biol. 2006 Oct;13(10):879-86. doi: 10.1038/nsmb1150. Epub 2006 Sep 24. Nat Struct Mol Biol. 2006. PMID: 16998486 Free PMC article.
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The antibiotic kasugamycin mimics mRNA nucleotides to destabilize tRNA binding and inhibit canonical translation initiation.Nat Struct Mol Biol. 2006 Oct;13(10):871-8. doi: 10.1038/nsmb1145. Epub 2006 Sep 24. Nat Struct Mol Biol. 2006. PMID: 16998488