Review
doi: 10.1016/0140-6736(91)93341-6.
FK 506: an immunosuppressant for the 1990s?
Affiliations
- PMID: 1702172
- DOI: 10.1016/0140-6736(91)93341-6
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Review
FK 506: an immunosuppressant for the 1990s?
Lancet.
.
Erratum in
- Lancet 1991 Apr 13;337(8746):928
Abstract
The novel macrolide immunosuppressant FK 506 is a powerful and selective anti-T-cell agent which has a similar mode of action to that of cyclosporin. Clinical studies of FK 506 in liver allograft recipients indicate a lower risk/benefit ratio than with cyclosporin, and wider evaluation of FK 506 in transplant recipients is now under way in multicentre, prospective, controlled trials in both Europe and North America.
Comment in
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Mechanism of action of FK 506 and cyclosporin.Lancet. 1991 Feb 16;337(8738):439. doi: 10.1016/0140-6736(91)91225-j. Lancet. 1991. PMID: 1704088 No abstract available.
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FK 506.Lancet. 1991 Feb 23;337(8739):499. doi: 10.1016/0140-6736(91)93441-b. Lancet. 1991. PMID: 1704090 No abstract available.
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