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Review
. 2006 Oct;45(10):1333-42; quiz 1343.
doi: 10.1007/s00120-006-1211-7.

[Managing the side effects of angiogenetic inhibitors in metastatic renal cell carcinoma]

[Article in German]
M Staehler  1 , N Haseke, G Schöppler, T Stadler, G Heinemann, C G Stief
Affiliations
Review

[Managing the side effects of angiogenetic inhibitors in metastatic renal cell carcinoma]

[Article in German]
M Staehler et al. Urologe A. 2006 Oct.

Abstract

Sunitinib and Sorafenib are both effective angiogenetic inhibitors for the treatment of renal cell carcinoma. With these drugs of a new class of chronic therapy is performed. During chronic treatment, the inherent side effects may necessitate stopping the application of these drugs thus preventing the required effective therapy. Most of the effects can be avoided or attenuated by prophylaxis. In this paper the published data are reviewed and added with our experience in 138 patients over up to two and a half years.

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References

    1. Eur Urol. 2004 Sep;46(3):327-30 - PubMed
    1. Eur Urol. 2005 Jul;48(1):77-81; discussion 81-2 - PubMed
    1. Curr Drug Targets. 2005 Nov;6(7):835-46 - PubMed
    1. Eur Urol. 2004 Oct;46(4):472-6 - PubMed
    1. Eur Urol. 2006 Feb;49(2):223-5 - PubMed

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