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Review
. 2006 Oct 7;333(7571):733-7.
doi: 10.1136/bmj.38975.390370.7C.

How to measure renal function in clinical practice

Jamie Traynor  1 , Robert Mactier, Colin C Geddes, Jonathan G Fox
Affiliations
Review

How to measure renal function in clinical practice

Jamie Traynor et al. BMJ. .
No abstract available

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Figures

Fig 1
Fig 1
Biphasic disappearance of injected substance from plasma. During the first phase, equilibration of the injected substance takes place between the intravascular and extravascular compartments (k2). Once equilibration has been reached, the decline in plasma levels (normally measured with a venous sample) should reflect removal of the substance from the arterial system through the kidneys. This is termed the terminal elimination phase (k1)
Fig 2
Fig 2
Commonly used formulas for estimating renal function. MDRD=modification of diet in renal disease
See this image and copyright information in PMC

Comment in

References

    1. Chantler C, Garnett ES, Parsons V, Veall N. Glomerular filtration rate measurement in man by the single injection methods using 51Cr-EDTA. Clin Sci 1969;37: 169-80. - PubMed
    1. Rehling M, Moller ML, Thamdrup B, Lund JO, Trap-Jensen J. Simultaneous measurement of renal clearance and plasma clearance of 99mTc-labelled diethylenetriaminepenta-acetate, 51Cr-labelled ethylenediaminetetra-acetate and inulin in man. Clin Sci (Lond) 1984;66: 613-9. - PubMed
    1. Israelit AH, Long DL, White MG, Hull AR. Measurement of glomerular filtration rate utilizing a single subcutaneous injection of 125Iiothalamate. Kidney Int 1973;4: 346-9. - PubMed
    1. Dondi M, Fanti S. Determination of individual renal function through noninvasive methodologies. Curr Opin Nephrol Hypertens 1995;4: 520-4. - PubMed
    1. Brochner-Mortensen J. Current status on assessment and measurement of glomerular filtration rate. Clin Physiol 1985;5: 1-17. - PubMed