EM49, a new peptide antibiotic IV. The structure of EM49
- PMID: 170240
- DOI: 10.7164/antibiotics.28.379
EM49, a new peptide antibiotic IV. The structure of EM49
Abstract
EM49 is a family of similar peptide antibiotics, each an octapeptide acylated with a beta-hydroxy fatty acid. This paper described the determination of the structure of the fatty acyl residue, the selective removal of this residue from the peptide portion of the molecule, and the sequential analysis of the peptide by the EDMAN method. The structure of EM49, 1, is derived by this degradation.
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