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Case Reports
. 2006 Oct 10;67(7):1265-7.
doi: 10.1212/01.wnl.0000238390.86304.4e.

Speech and language delay are early manifestations of juvenile-onset Huntington disease

G Yoon  1 , J Kramer, A Zanko, M Guzijan, S Lin, A Foster-Barber, A L Boxer
Affiliations
Case Reports

Speech and language delay are early manifestations of juvenile-onset Huntington disease

G Yoon et al. Neurology. .

Abstract

The neurocognitive features of juvenile-onset Huntington disease (HD) are not well understood. We present three patients with onset of HD symptoms before age 10 years in whom speech delay was the first symptom. Speech delay predated motor symptoms by at least 2 years, and language function was consistently impaired on formal testing. Screening for speech delay is particularly important in children with a family history of HD.

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