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Review
. 2007 Mar;453(6):753-62.
doi: 10.1007/s00424-006-0153-7. Epub 2006 Oct 10.

Regulation of TRP channels by PIP(2)

Tibor Rohacs  1
Affiliations
Review

Regulation of TRP channels by PIP(2)

Tibor Rohacs. Pflugers Arch. 2007 Mar.

Abstract

Transient receptor potential (TRP) channels are regulated by a wide variety of physical and chemical factors. Recently, several members of the TRP channel family were reported to be regulated by phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P(2), PIP(2)). This review will summarize the current knowledge on PIP(2) regulation of TRP channels and discuss the possibility that PIP(2) is a common regulator of mammalian TRP channels.

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