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Comparative Study
. 1975 Sep;2(3):157-61.
doi: 10.1128/jcm.2.3.157-161.1975.

Measurement of parainfluenza-3 virus antibody by the single radial hemolysis technique

M Probert, S M Russell
Comparative Study

Measurement of parainfluenza-3 virus antibody by the single radial hemolysis technique

M Probert et al. J Clin Microbiol. 1975 Sep.

Abstract

A single radial hemolysis assay for parainfluenza-3 virus antibody is described as a simple, sensitive, accurate, and precise alternative to hemagglutination inhibition and serum neutralization tests. A highly significant correlation exists between single radial hemolysis zone areas and hemagglutination inhibition titers of both serum and nasal secretion samples. Antibody conversions equivalent to as little as a twofold rise in hemagglutination inhibition titer are readily and reliably detected in sera and nasal secretions. Single radial hemolysis and hemagglutination inhibition activity was demonstrable in the immunoglobulin G fraction of a hyperimmune parainfluenza-3 virus antiserum.

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References

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