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Review
. 2006 Oct 16:4:37.
doi: 10.1186/1476-7120-4-37.

C-reactive protein in aortic valve disease

Pedro L Sanchez  1 , Anna Maria Mazzone
Affiliations
Review

C-reactive protein in aortic valve disease

Pedro L Sanchez et al. Cardiovasc Ultrasound. .

Retraction in

Abstract

Aortic Valve Disease, includes a range of disorder severity from mild leaflet thickening without valve obstruction, "aortic sclerosis", to severe calcified aortic stenosis. It is a slowly progressive active process of valve modification similar atherosclerosis for cardiovascular risk factors, lipoprotein deposition, chronic inflammation, and calcification. Systemic signs of inflammation, as wall and serum CRP, similar to those found in atherosclerosis, are present in patients with degenerative aortic valve stenosis and may be expression of a common disease, useful in monitoring of stenosis progression.

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Figures

Figure 1
Figure 1
Rate of CRP > 3 mg/L in patients with slow and rapid aortic stenosis progression according to the assesment of aortic jet velocity (Cw). Slow and rapid progressors were considered those patients with an increase in aortic jet velocity < or ≥ 0.15 m/s respectively, during the six months follow-up.
Figure 2
Figure 2
Rate of CRP > 3 mg/L in patients with slow and rapid aortic stenosis progression according to the assesment of the aortic valve area (AVA). Slow and rapid progressors were considered those patients with a decrease in AVA < or ≥ 0.05 cm2 respectively, during the six months follow-up.
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