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. 2007 Mar;65(3):318-27.
doi: 10.1016/j.apradiso.2006.08.009. Epub 2006 Oct 11.

A new internal pair production branching ratio of 90Y: the development of a non-destructive assay for 90Y and 90Sr

R G Selwyn  1 , R J Nickles, B R Thomadsen, L A DeWerd, J A Micka
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A new internal pair production branching ratio of 90Y: the development of a non-destructive assay for 90Y and 90Sr

R G Selwyn et al. Appl Radiat Isot. 2007 Mar.

Abstract

(90)Y is utilized as a therapeutic radioisotope in radiolabeled monoclonal antibodies and in microspheres for targeted radiation therapy of the liver. Currently, the widely used dose calibrator assay of (90)Y can have uncertainties exceeding +/-10%. A non-destructive assay using spectroscopy is possible by reducing the currently published uncertainty (+/-12%) in the internal pair production branching ratio for the 0(+)-0(+) transition of (90)Zr. A high-purity germanium detector was used to determine the branching ratio to be (31.86+/-0.47) x 10(-6).

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