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. 2006;2006(3):74539.
doi: 10.1155/JBB/2006/74539.

Tau phosphorylation, aggregation, and cell toxicity

J Avila  1 , I Santa-María, M Pérez, F Hernández, F Moreno
Affiliations

Tau phosphorylation, aggregation, and cell toxicity

J Avila et al. J Biomed Biotechnol. 2006.

Abstract

Protein aggregation takes place in many neurodegenerative disorders. However, there is a controversy about the possible toxicity of these protein aggregates. In this review, this controversy is discussed, focussing on the tau aggregation that takes place in those disorders known as tauopathies.

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