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. 2006 Nov 4:(41):4318-20.
doi: 10.1039/b610461d. Epub 2006 Sep 5.

Directed evolution of hybrid enzymes: Evolving enantioselectivity of an achiral Rh-complex anchored to a protein

Manfred T Reetz  1 , Jérôme J-P Peyralans, Andrea Maichele, Yu Fu, Matthias Maywald
Affiliations

Directed evolution of hybrid enzymes: Evolving enantioselectivity of an achiral Rh-complex anchored to a protein

Manfred T Reetz et al. Chem Commun (Camb). .

Abstract

The concept of utilizing the methods of directed evolution for tuning the enantioselectivity of synthetic achiral metal-ligand centers anchored to proteins has been implemented experimentally for the first time.

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