Review
doi: 10.1111/j.1365-2958.1990.tb02051.x.
Triple post-transcriptional control
Affiliations
- PMID: 1704997
- DOI: 10.1111/j.1365-2958.1990.tb02051.x
Item in Clipboard
Review
Triple post-transcriptional control
Mol Microbiol.
1990 Sep.
Abstract
The ermC gene confers resistance to MLS antibiotics in a Bacillus subtilis host. Synthesis of the ermC gene product, a ribosomal RNA methylase, is inducible by the addition of subinhibitory concentrations of erythromycin. Regulation of ermC gene expression occurs at the post-transcriptional level in three ways: translational attenuation, translational autoregulation, and messenger RNA stabilization.
Similar articles
-
Translational attenuation: the regulation of bacterial resistance to the macrolide-lincosamide-streptogramin B antibiotics.CRC Crit Rev Biochem. 1984;16(2):103-32. doi: 10.3109/10409238409102300. CRC Crit Rev Biochem. 1984. PMID: 6203682 Review.
-
Translational autoregulation of ermC 23S rRNA methyltransferase expression in Bacillus subtilis.J Bacteriol. 1986 Dec;168(3):1133-41. doi: 10.1128/jb.168.3.1133-1141.1986. J Bacteriol. 1986. PMID: 3096970 Free PMC article.
-
Identification of cis-acting sequences required for translational autoregulation of the ermC methylase.J Bacteriol. 1990 Jul;172(7):3661-8. doi: 10.1128/jb.172.7.3661-3668.1990. J Bacteriol. 1990. PMID: 2113909 Free PMC article.
-
Role of mRNA termination in regulation of ermK.J Bacteriol. 1997 Mar;179(6):2065-7. doi: 10.1128/jb.179.6.2065-2067.1997. J Bacteriol. 1997. PMID: 9068656 Free PMC article.
-
Genetic control by metabolite-binding riboswitches.Chembiochem. 2003 Oct 6;4(10):1024-32. doi: 10.1002/cbic.200300685. Chembiochem. 2003. PMID: 14523920 Review. No abstract available.
Cited by
-
Polycysteine-encoding leaderless short ORFs function as cysteine-responsive attenuators of operonic gene expression in mycobacteria.Mol Microbiol. 2020 Jul;114(1):93-108. doi: 10.1111/mmi.14498. Epub 2020 Apr 9. Mol Microbiol. 2020. PMID: 32181921 Free PMC article.
-
RNA processing and degradation in Bacillus subtilis.Microbiol Mol Biol Rev. 2003 Jun;67(2):157-74, table of contents. doi: 10.1128/MMBR.67.2.157-174.2003. Microbiol Mol Biol Rev. 2003. PMID: 12794188 Free PMC article. Review.
-
Translation of the mRNA for the sporulation gene spoIIID of Bacillus subtilis is dependent upon translation of a small upstream open reading frame.J Bacteriol. 1997 Feb;179(4):1324-8. doi: 10.1128/jb.179.4.1324-1328.1997. J Bacteriol. 1997. PMID: 9023218 Free PMC article.
-
Screening for inhibitors of the SOD1 gene promoter: pyrimethamine does not reduce SOD1 levels in cell and animal models.Neurosci Lett. 2010 Oct 4;482(3):188-92. doi: 10.1016/j.neulet.2010.07.020. Epub 2010 Jul 16. Neurosci Lett. 2010. PMID: 20638444 Free PMC article.
-
Genetic and transcriptional analysis of flgB flagellar operon constituents in the oral spirochete Treponema denticola and their heterologous expression in enteric bacteria.Infect Immun. 1997 Jun;65(6):2041-51. doi: 10.1128/iai.65.6.2041-2051.1997. Infect Immun. 1997. PMID: 9169730 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Molecular Biology Databases
