Triple post-transcriptional control
- PMID: 1704997
- DOI: 10.1111/j.1365-2958.1990.tb02051.x
Triple post-transcriptional control
Abstract
The ermC gene confers resistance to MLS antibiotics in a Bacillus subtilis host. Synthesis of the ermC gene product, a ribosomal RNA methylase, is inducible by the addition of subinhibitory concentrations of erythromycin. Regulation of ermC gene expression occurs at the post-transcriptional level in three ways: translational attenuation, translational autoregulation, and messenger RNA stabilization.
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