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. 1991 Mar;11(3):1739-44.
doi: 10.1128/mcb.11.3.1739-1744.1991.

Tst-1, a member of the POU domain gene family, binds the promoter of the gene encoding the cell surface adhesion molecule P0

X He  1 , R Gerrero, D M Simmons, R E Park, C J Lin, L W Swanson, M G Rosenfeld
Affiliations

Tst-1, a member of the POU domain gene family, binds the promoter of the gene encoding the cell surface adhesion molecule P0

X He et al. Mol Cell Biol. 1991 Mar.

Abstract

Tst-1, a member of the POU domain gene family, is expressed in specific neurons and in myelinating glia in the mammalian nervous system. Bacterially expressed Tst-1 binds specifically to the promoter of the gene encoding myelin protein P0, a Schwann cell surface adhesion molecule. In cotransfection assays, Tst-1 can specifically repress the P0 promoter. The N-terminal part of Tst-1 protein is highly glycine- and alanine-rich, a structural feature shared by the helix-loop-helix protein TFEB.

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References

    1. Proc Natl Acad Sci U S A. 1990 Mar;87(6):2289-93 - PubMed
    1. Science. 1990 Sep 14;249(4974):1300-3 - PubMed
    1. Genes Dev. 1990 May;4(5):695-711 - PubMed
    1. Proc Natl Acad Sci U S A. 1977 Dec;74(12):5463-7 - PubMed
    1. EMBO J. 1990 Nov;9(11):3723-32 - PubMed

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