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Randomized Controlled Trial
. 2007 Mar;13(2):115-21.
doi: 10.1016/j.parkreldis.2006.07.007. Epub 2006 Oct 20.

Effectiveness of physiotherapy in Parkinson's disease: the feasibility of a randomised controlled trial

S H J Keus  1 , B R Bloem, J J van Hilten, A Ashburn, M Munneke
Affiliations
Randomized Controlled Trial

Effectiveness of physiotherapy in Parkinson's disease: the feasibility of a randomised controlled trial

S H J Keus et al. Parkinsonism Relat Disord. 2007 Mar.

Abstract

To study the feasibility of a large randomised controlled trial (RCT) evaluating the effectiveness of physiotherapy in Parkinson's disease (PD), 173 patients were asked to participate in a study with random allocation to best practice physiotherapy, or to no physiotherapy. The primary outcome measures were the Parkinson's disease questionnaire-39, the Parkinson activity scale, and a patient preference outcome scale (PPOS). Only 14% of the patients could be included in the study. The PPOS showed the largest effect size (0.74) with a significant group effect (p<0.05). Specific alterations to the study design to ensure successful RCTs in this field are recommended.

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