Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1991 Jan;225(1):158-67.
doi: 10.1007/BF00282654.

The mitochondrial genome of fission yeast: inability of all introns to splice autocatalytically, and construction and characterization of an intronless genome

B Schäfer  1 , A M Merlos-Lange, C Anderl, F Welser, M Zimmer, K Wolf
Affiliations

The mitochondrial genome of fission yeast: inability of all introns to splice autocatalytically, and construction and characterization of an intronless genome

B Schäfer et al. Mol Gen Genet. 1991 Jan.

Abstract

In this paper we report the inability of four group I introns in the gene encoding subunit I of cytochrome c oxidase (cox1) and the group II intron in the apocytochrome b gene (cob) to splice autocatalytically. Furthermore we present the characterization of the first cox1 intron in the mutator strain anar-14 and the construction and characterization of strains with intronless mitochondrial genomes. We provide evidence that removal of introns at the DNA level (termed DNA splicing) is dependent on an active RNA maturase. Finally we demonstrate that the absence of introns does not abolish homologous mitochondrial recombination.

PubMed Disclaimer

References

    1. Cell. 1985 Apr;40(4):759-66 - PubMed
    1. Curr Genet. 1987;12(5):329-36 - PubMed
    1. Mol Gen Genet. 1989 May;217(1):168-71 - PubMed
    1. Biochimie. 1982 Oct;64(10):867-81 - PubMed
    1. J Bacteriol. 1972 May;110(2):667-76 - PubMed

Publication types

LinkOut - more resources