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. 2006 Oct;22(10):931-5.
doi: 10.1089/aid.2006.22.931.

Proposal for diagnostic criteria of tropical spastic paraparesis/HTLV-I-associated myelopathy (TSP/HAM)

Carlos M De Castro-Costa  1 , Abelardo Q C Araújo, Márcio M Barreto, Osvaldo M Takayanagui, Marzia P Sohler, Eduardo L M da Silva, Sônia M B de Paula, Ricardo Ishak, João G R Ribas, Luis C Rovirosa, Herwig Carton, Eduardo Gotuzzo, William W Hall, Silvia Montano, Edward L Murphy, Joel Oger, Carlos Remondegui, Graham P Taylor
Affiliations

Proposal for diagnostic criteria of tropical spastic paraparesis/HTLV-I-associated myelopathy (TSP/HAM)

Carlos M De Castro-Costa et al. AIDS Res Hum Retroviruses. 2006 Oct.

Abstract

After the first description of TSP/HAM in 1985 and the elaboration of WHO's diagnostic criteria in 1988, the experience of the professionals in this field has increased so that a critical reappraisal of these diagnostic guidelines was considered timely. Brazilian neurologists and observers from other countries met recently to discuss and propose a modified model for diagnosing TSP/HAM with levels of ascertainment as definite, probable, and possible, according to myelopathic symptoms, serological findings, and/or detection of HTLV-I DNA and exclusion of other disorders.

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