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Case Reports
. 2007 Feb;36(4):262-3.
doi: 10.1016/j.semarthrit.2006.08.004. Epub 2006 Oct 25.

Toxoplasmic chorioretinitis and antitumor necrosis factor treatment in rheumatoid arthritis

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Case Reports

Toxoplasmic chorioretinitis and antitumor necrosis factor treatment in rheumatoid arthritis

Slim Lassoued et al. Semin Arthritis Rheum. 2007 Feb.

Abstract

Objectives: To present the data supporting the possible relationship of ocular toxoplasmosis to antitumor necrosis factor-alpha (TNF-alpha) therapy in patients with rheumatoid arthritis (RA).

Methods: A Medline search was performed using the words "toxoplasmosis, anti-TNF-alpha antagonists, chorioretinitis." We report 2 RA patients who developed ocular toxoplasmosis while receiving anti-TNF-alpha therapy.

Results: In addition to our patients with toxoplasmic chorioretinitis, there are 2 published cases of cerebral toxoplasmosis during treatment with anti-TNF-alpha agents.

Conclusion: The risk of serious toxoplasmic infection during anti-TNF-alpha therapy for RA should be recognized.

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