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Review
. 2007 Jan;59(1):1-4.
doi: 10.1093/jac/dkl429. Epub 2006 Oct 26.

The potential clinical impact of low-level antibiotic resistance in Staphylococcus aureus

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Review

The potential clinical impact of low-level antibiotic resistance in Staphylococcus aureus

F Goldstein. J Antimicrob Chemother. 2007 Jan.

Abstract

Low-level antibiotic resistance in Staphylococcus aureus is a frequently overlooked phenomenon, usually not detected by standard susceptibility testing procedures. It represents a gateway to high-level clinically relevant resistance. Moreover, low-level resistance may be associated with increased virulence, resistance to unrelated compounds and more successful in vivo survival.

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