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Comparative Study
. 2006 Oct;77(5):788-90.
doi: 10.1080/17453670610013006.

C-reactive protein as a parameter of surgical trauma: CRP response after different types of surgery in 349 hip fractures

Affiliations
Comparative Study

C-reactive protein as a parameter of surgical trauma: CRP response after different types of surgery in 349 hip fractures

Markus Neumaier et al. Acta Orthop. 2006 Oct.

Abstract

Background: Postoperative C-reactive protein (CRP) levels in serum appear to reflect surgical trauma. We examined CRP levels after different types of surgery in hip fractures.

Methods: We studied the CRP response after 349 operative procedures in proximal femur fractures with a normal postoperative course. 5 different operative techniques were used: 3-4 percutaneous cancellous screws, dynamic hip screw (DHS), proximal femur nail (PFN), hemiarthroplasty (HA), and total hip arthroplasty (THA).

Results: Peak CRP levels were reached on the second postoperative day in each group (medians: screws 8.7, DHS 12, PFN 14, HA 16, THA 16 mg/dL). Significant differences were found between screws and all others, and between DHS and arthroplasties.

Interpretation: CRP levels following surgical trauma can be used to quantify the degree of tissue damage and invasiveness of a procedure and reflect the perioperative stress experienced by the patient.

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