Review
doi: 10.1016/j.bbamem.2006.09.011.
Epub 2006 Sep 23.
Biophysics of sphingolipids I. Membrane properties of sphingosine, ceramides and other simple sphingolipids
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- PMID: 17070498
- DOI: 10.1016/j.bbamem.2006.09.011
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Review
Biophysics of sphingolipids I. Membrane properties of sphingosine, ceramides and other simple sphingolipids
Biochim Biophys Acta.
2006 Dec.
Free article
Erratum in
- Biochim Biophys Acta. 2007 May;1768(5):1309-10
Abstract
Some of the simplest sphingolipids, namely sphingosine, ceramide, some closely related molecules (eicosasphingosine, phytosphingosine), and their phosphorylated compounds (sphingosine-1-phosphate, ceramide-1-phosphate), are potent metabolic regulators. Each of these lipids modifies in marked and specific ways the physical properties of the cell membranes, in what can be the basis for some of their physiological actions. This paper reviews the mechanisms by which these sphingolipid signals, sphingosine and ceramide in particular, are able to modify the properties of cell membranes.
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