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. 1975 Jun 23;367(1):73-81.
doi: 10.1007/BF00430774.

Morphogenesis of intracytoplasmic dense (inclusion) bodies in a recurring digital fibrous tumor of childhood. Light- and electron-microscopic investigations

D Stiller, D Katenkamp

Morphogenesis of intracytoplasmic dense (inclusion) bodies in a recurring digital fibrous tumor of childhood. Light- and electron-microscopic investigations

D Stiller et al. Virchows Arch A Pathol Anat Histol. .

Abstract

This study presents the results of light-microscopic, histochemical, and electron-microscopic investigations of dense (inclusion) bodies in a recurring digital fibrous tumor of childhood. At ultrastructural level it was possible to observe several stages of development correlated with changes of ergastoplasmic reticulum. The viral nature of these bodies was refuted and the conclusion was drawn that their formation is associated with a disturbed intracellular metabolism. The defective intracellular transport of collagen precursors followed by abnormal deposition of collagenous proteins, which are also to some extent abnormally aggregated, could be of special importance.

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References

    1. Arch Dermatol. 1969 Jan;99(1):37-42 - PubMed
    1. Arch Dermatol. 1972 Sep;106(3):375-8 - PubMed
    1. Acta Pathol Microbiol Scand A. 1973 Mar;81(2):167-73 - PubMed
    1. Ergeb Anat Entwicklungsgesch. 1956;35:240-333 - PubMed
    1. Arch Pathol. 1965 Sep;80:228-31 - PubMed