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. 2007 Mar;42(3):425-9.
doi: 10.1016/j.ejmech.2006.09.010. Epub 2006 Oct 30.

Synthesis of some bioactive 2-bromo-5-methoxy-N'-[4-(aryl)-1,3-thiazol-2-yl]benzohydrazide derivatives

K K Vijaya Raj  1 , B Narayana, B V Ashalatha, N Suchetha Kumari, B K Sarojini
Affiliations

Synthesis of some bioactive 2-bromo-5-methoxy-N'-[4-(aryl)-1,3-thiazol-2-yl]benzohydrazide derivatives

K K Vijaya Raj et al. Eur J Med Chem. 2007 Mar.

Abstract

Eight novel 2-bromo-5-methoxy-N'-[4-(aryl)-1,3-thiazol-2-yl]benzohydrazide derivatives were prepared and characterized by analytical and spectral analyses. All the compounds were screened for their analgesic, antifungal and antibacterial activities and three of the compounds were screened for antiproliferative activity. Two of the newly synthesized compounds exhibited promising analgesic activity and one compound exhibited in vitro antiproliferative activity.

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