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. 1990 Nov;31(3-4):317-20.
doi: 10.1007/BF01997626.

Effect of substance P on the membrane potential of coronary arterial endothelial cells in situ

J L Bény  1
Affiliations

Effect of substance P on the membrane potential of coronary arterial endothelial cells in situ

J L Bény. Agents Actions. 1990 Nov.

Abstract

The membrane potential of the endothelial cells on a strip of pig coronary artery was recorded. The fluorescent dye lucifer yellow was injected into the recorded cell in order to prove its identity. We show that substance P transiently hyperpolarized these cells. The function of the endothelial cell hyperpolarization could be important for the role played by the endothelium and the kinins in inflammation.

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References

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