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Comment
. 2006 Oct;3(10):e432.
doi: 10.1371/journal.pmed.0030432.

Complement factor h gene abnormalities in haemolytic uraemic syndrome: from point mutations to hybrid gene

Marina Noris  1 , Giuseppe Remuzzi
Affiliations
Comment

Complement factor h gene abnormalities in haemolytic uraemic syndrome: from point mutations to hybrid gene

Marina Noris et al. PLoS Med. 2006 Oct.

Abstract

Noris and Remuzzi discuss a new study showing an association between atypical haemolytic uremic syndrome and a hybrid complement gene,CFH/CFHL1.

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Conflict of interest statement

Competing Interests: The authors have declared that no competing interests exist.

Comment on

References

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    1. Caprioli J, Noris M, Brioschi S, Pianetti G, Castelletti F, et al. Genetics of HUS: The impact of MCP, CFH and IF mutations on clinical presentation, response to treatment and outcome. Blood. 2006;108:1267–1279. - PMC - PubMed
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    1. Zipfel PF, Jokiranta TS, Hellwage J, Koistinen V, Meri S. The factor H protein family. Immunopharmacology. 1999;42:53–60. - PubMed

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