Can the severity of normal tissue damage after radiation therapy be predicted?
- PMID: 17076565
- PMCID: PMC1626559
- DOI: 10.1371/journal.pmed.0030440
Can the severity of normal tissue damage after radiation therapy be predicted?
Abstract
Begg discusses a new study by Svensson and colleagues in which the researchers attempted to elucidate genetic factors involved in late radiation toxicity.
Conflict of interest statement
Comment on
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Analysis of gene expression using gene sets discriminates cancer patients with and without late radiation toxicity.PLoS Med. 2006 Oct;3(10):e422. doi: 10.1371/journal.pmed.0030422. PLoS Med. 2006. PMID: 17076557 Free PMC article.
References
-
- Norman A, Kagan AR, Chan SL. The importance of genetics for the optimization of radiation therapy. A hypothesis. Am J Clin Oncol. 1988;11:84–88. - PubMed
-
- Bentzen SM. Preventing or reducing late side effects of radiation therapy: Radiobiology meets molecular pathology. Nat Rev Cancer. 2006;6:702–713. - PubMed
-
- Hoeller U, Borgmann K, Bonacker M, Kuhlmey A, Bajrovic A, et al. Individual radiosensitivity measured with lymphocytes may be used to predict the risk of fibrosis after radiotherapy for breast cancer. Radiother Oncol. 2003;69:137–144. - PubMed
-
- Lee TK, Allison RR, O'Brien KF, Johnke RM, Christie KI, et al. Lymphocyte radiosensitivity correlated with pelvic radiotherapy morbidity. Int J Radiat Oncol Biol Phys. 2003;57:222–229. - PubMed
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