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Review
. 2007 Apr;81(7):3051-7.
doi: 10.1128/JVI.01466-06. Epub 2006 Nov 1.

The novel human coronaviruses NL63 and HKU1

Krzysztof Pyrc  1 , Ben Berkhout, Lia van der Hoek
Affiliations
Review

The novel human coronaviruses NL63 and HKU1

Krzysztof Pyrc et al. J Virol. 2007 Apr.
No abstract available

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Figures

FIG. 1.
FIG. 1.
Schematic organization of the HCoV-NL63 and HCoV-HKU1 genomes. All ORFs and the 3′ and 5′ untranslated regions (UTR) are marked. Below the scheme, the corresponding subgenomic (sg) mRNAs generated during the discontinuous transcription process are shown (putative for HCoV-HKU1). RFS represents the putative ribosomal frameshifting element between the 1a and 1b genes.
FIG. 2.
FIG. 2.
Schematic representation of the spike protein of HCoV-NL63 and HCoV-HKU1. The signal peptide was identified by using the SignalIP 3.0 server (4, 53). The border between the S1 and S2 domains corresponds to the predicted furin-like enzyme cleavage site identified with the ProP 1.0 server (17). The yellow dots represent N-glycosylation sites predicted with the NetNGlyc1.0 server (R. Gupta, E. Jung, and S. Brunak, unpublished data). Heptad repeat regions (HR1 and HR2) were identified by using protein alignments. The transmembrane domain was identified with the TMHMM 2.0 server (39, 66).
See this image and copyright information in PMC

References

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    1. Bendtsen, J. D., H. Nielsen, G. von Heijne, and S. Brunak. 2004. Improved prediction of signal peptides: SignalP 3.0. J. Mol. Biol. 340:783-795. - PubMed
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