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. 2007 Jan;14(1):85-6.
doi: 10.1128/CVI.00253-06. Epub 2006 Nov 1.

Dynamics of Helicobacter pylori-specific immunoglobulin G for 2 years after successful eradication of Helicobacter pylori infection in an American Indian and Alaska Native population

Karen M Miernyk  1 , Dana L Bruden, Michael G Bruce, Brian J McMahon, Thomas W Hennessy, Helen V Peters, Debby A Hurlburt, Frank Sacco, Alan J Parkinson
Affiliations

Dynamics of Helicobacter pylori-specific immunoglobulin G for 2 years after successful eradication of Helicobacter pylori infection in an American Indian and Alaska Native population

Karen M Miernyk et al. Clin Vaccine Immunol. 2007 Jan.

Abstract

Helicobacter pylori antibodies were measured over 24 months in American Indian and Alaska Native persons who cleared their infections. Two months after treatment, 82% of H. pylori-negative persons remained seropositive. While there were declines in H. pylori antibodies for 12 months, after 24 months 71% of persons remained seropositive.

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Figures

FIG. 1.
FIG. 1.
Mean H. pylori-specific (anti-Hp) IgG ODs (measured at 0, 2, 4, 6, 12, and 24 months posttreatment) for 104 patients in follow-up after successful H. pylori eradication. Participants are categorized by the quartiles of their pretreatment H. pylori-specific IgG ODs. The percent decline in H. pylori-specific IgG OD from time zero to 24 months is indicated for each quartile. Data were obtained in Anchorage, AK, 1998-2002. For persons reinfected with H. pylori, the H. pylori-specific IgG OD was removed from the data beginning from the visit where reinfection was detected.
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